GnRH agonist for luteal support in IVF? Setting the balance between enthusiasm and caution.

نویسندگان

  • Cornelis B Lambalk
  • Roy Homburg
چکیده

2580 © The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: [email protected] Associate editor’s commentary on ‘Beneficial effect of luteal-phase GnRH agonist administration on embryo implantation after ICSI in both GnRH agonistand antagonist-treated ovarian stimulation cycles’ by Tesarik et al.

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I-27: GnRH Agonist Triggering and Luteal Phase Support

Background GnRH agonist triggering is one of the strategies for ovulation triggering and final maturation of oocytes. So , should be notice for luteal phase support in these cycles. At the first it was began for prevention of severe OHSS but it was associated with luteal phase problem and lower pregnancy rate due to luteolysis effects of GnRH agonists. So, two other alternative strategies have ...

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P-160: A Comparative Study of Luteal Estradiol Pre-Treatment in GnRH Antagonist Protocols AndIn Micro Dose Flare Protocols for Poor Responding Patients

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Endometrial gene expression in the early luteal phase is impacted by mode of triggering final oocyte maturation in recFSH stimulated and GnRH antagonist co-treated IVF cycles.

STUDY QUESTION Do differences in endometrial gene expression exist after ovarian stimulation with four different regimens of triggering final oocyte maturation and luteal phase support in the same patient? SUMMARY ANSWER Significant differences in the expression of genes involved in receptivity and early implantation were seen between the four protocols. WHAT IS KNOWN ALREADY GnRH agonist t...

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Addition of gonadotropin releasing hormone agonist for luteal phase support in in-vitro fertilization: an analysis of 2739 cycles.

OBJECTIVE Luteal phase is defective in in vitro fertilization (IVF) cycles, and many regimens were tried for the very best luteal phase support (LPS). Gonadotropin releasing hormone (GnRH) agonist use, which was administered as an adjunct to the luteal phase support in IVF cycles, was suggested to improve pregnancy outcome measures in certain randomized studies. We analyzed the effects of addit...

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Lower levels of inhibin A and pro-alphaC during the luteal phase after triggering oocyte maturation with a gonadotropin-releasing hormone agonist versus human chorionic gonadotropin.

OBJECTIVE To investigate the effect of triggering oocyte maturation with GnRH agonist on corpus luteum function by measuring luteal phase levels of inhibin A and pro-alphaC. DESIGN Prospective randomized trial. SETTING In vitro fertilization (IVF) program at a university hospital. PATIENT(S) Infertile women undergoing IVF-ET treatment. INTERVENTION(S) Controlled ovarian hyperstimulation...

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عنوان ژورنال:
  • Human reproduction

دوره 21 10  شماره 

صفحات  -

تاریخ انتشار 2006